Cell Signaling
A 16-module path through cell signaling, in study order from foundations to the frontier.
Modules
- Principles of Cell Signaling
- Signal Types: Endocrine, Paracrine, Autocrine
- Receptor Classes: An Overview
- Intracellular Receptors and Hydrophobic Signals
- G-Protein-Coupled Receptor Architecture
- Heterotrimeric G Proteins as Molecular Switches
- cAMP Second Messenger Pathway
- The Phosphoinositide Pathway: IP3 and DAG
- Calcium as an Intracellular Messenger
- Receptor Tyrosine Kinase Architecture
- RTK Activation: Dimerization and Autophosphorylation
- Adaptor Proteins and Ras Activation
- The MAP Kinase Cascade
- Signal Amplification and the Cascade Concept
- Signal Integration and Crosstalk
- Apoptosis Signaling: Extrinsic and Intrinsic Pathways