Pattern Formation & Axis Specification
A 18-module path through pattern formation & axis specification, in study order from foundations to the frontier.
Modules
- Positional Information
- Morphogen Gradients
- The French-Flag Model
- Threshold Responses and Gene Expression
- Anterior-Posterior Axis Specification
- Maternal-Effect Genes and Cytoplasmic Determinants
- The Bicoid Gradient in Drosophila
- The Segmentation Gene Hierarchy
- Hox Genes and the Body Plan
- Homeotic Transformations and Colinearity
- Evo-Devo and Conservation of Hox Clusters
- Dorsal-Ventral Patterning in Drosophila
- Induction and Competence
- The Spemann-Mangold Organizer
- Organizer Molecules and Antagonist Gradients
- Lateral Inhibition and Notch Signaling
- Secondary Signaling Centers
- Left-Right Asymmetry