Mutation & Molecular Genetics
A 16-module path through mutation & molecular genetics, in study order from foundations to the frontier.
Modules
- The Nature of Mutation
- Point Mutations and Base Substitutions
- Silent, Missense, and Nonsense Mutations
- Frameshift Mutations
- Spontaneous versus Induced Mutation
- Mutagens and the Ames Test
- The Luria-Delbruck Fluctuation Test
- DNA Transposons and Retrotransposons
- Forward versus Reverse Genetics
- Restriction Enzymes and DNA Cutting
- Molecular Cloning and Recombinant DNA
- The Polymerase Chain Reaction
- Sanger Dideoxy Sequencing
- Next-Generation Sequencing Overview
- Gene Knockouts and Loss-of-Function Analysis
- CRISPR-Cas9 Genome Editing