DNA Replication & Repair
A 18-module path through dna replication & repair, in study order from foundations to the frontier.
Modules
- Semiconservative Replication and the Meselson–Stahl Experiment
- Origins of Replication and the Replication Bubble
- The Replication Fork and Strand Separation
- DNA Polymerases and 5' to 3' Synthesis
- Primase and the RNA Primer
- Leading and Lagging Strand Synthesis
- Okazaki Fragment Maturation and DNA Ligase
- The Replisome: An Integrated Replication Machine
- Proofreading and Replication Fidelity
- The End-Replication Problem
- Telomeres and Telomerase
- DNA Damage and Mutation: An Overview
- Mismatch Repair
- Base Excision Repair
- Nucleotide Excision Repair
- Double-Strand Break Repair Pathways
- Homologous Recombination
- Translesion Synthesis