Translation & Protein Fate
A 16-module path through translation & protein fate, in study order from foundations to the frontier.
Modules
- Deciphering the Genetic Code
- Properties of the Genetic Code
- Transfer RNA Structure
- The Wobble Hypothesis
- Aminoacyl-tRNA Synthetases and the Second Genetic Code
- Ribosome Structure and Function
- The Ribosome as a Ribozyme
- Translation Initiation in Bacteria
- Translation Initiation in Eukaryotes
- Elongation and Codon Recognition
- Peptide Bond Formation and Peptidyl Transferase
- Translocation and the Elongation Cycle
- Termination and Release Factors
- Polysomes and Translational Efficiency
- Protein Folding and Molecular Chaperones
- The Ubiquitin-Proteasome System