Amines & Nitrogen Chemistry
A 20-module path through amines & nitrogen chemistry, in study order from foundations to the frontier.
Modules
- Structure and Hybridization of Amines
- Amine Nomenclature and Classification
- Chirality and Nitrogen Inversion
- Basicity of Amines: The Core Principle
- Inductive and Hybridization Effects on Basicity
- Aromatic Amines: Reduced Basicity
- Ring Substituent Effects on Aniline Basicity
- Basicity of Nitrogen Heterocycles
- Amines as Nucleophiles
- The Overalkylation Problem in Direct Alkylation
- Gabriel Synthesis of Primary Amines
- Reductive Amination
- Reduction of Nitriles and Amides to Amines
- Acylation of Amines to Amides
- Amines as Protecting/Activating Groups in EAS
- Diazonium Salt Formation (Diazotization)
- Diazonium Substitution Reactions
- Azo Coupling
- Aromatic Amines and Azo Dyes
- The Hofmann Elimination