In a normal-phase column chromatography run with silica as the stationary phase

CHEMISTRY · Subjective · A Level · Chemistry · Chromatography · Chromatography

Problem

In a normal-phase column chromatography run with silica as the stationary phase, compound A elutes at 3.2 min and compound B at 6.5 min. Compound A contains a carbonyl group but no hydrogen-bond donors, whereas compound B contains both a carbonyl group and an –OH group. In one sentence, explain why compound B elutes later than compound A.

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