Biologists model the mass (in grams) of a bacterial culture over time using

MATHEMATICS · Multi-part · A Level · Mathematics · Exponentials and logarithms · Exponentials and logarithms

Problem

Biologists model the mass (in grams) of a bacterial culture over time using M(t)=Ae−ktM(t)=A e^{-k t}, where AA is the initial mass and k>0k>0 is an unknown decay rate. The culture is measured every hour for six hours; the data are recorded below.
Time tt (h)0123456
Measured mass MobsM_{\text{obs}} (g)5.003.953.102.461.941.561.25
Because the initial reading is precise, set A=5.00 gA=5.00\text{ g}. You must determine the decay rate kk that best matches the remaining observations. (a) Write an explicit expression S(k)S(k) for the total squared deviation between the model M(t)=5.00e−ktM(t)=5.00 e^{-k t} and the observed masses for t=1t=1 through t=6t=6. (b) Derive S′(k)S'(k) and set it equal to zero. Show all calculus steps leading to an equation that the optimal kk satisfies. (c) Using technology or justified numerical estimation, solve the equation from part (b) to three decimal places. State the value of kk with appropriate units. (d) Based on your value of kk, predict the culture’s mass at t=8 ht=8\text{ h}. Comment on the reliability of this prediction, considering the spacing of the data and the exponential model.

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