Biologists model the mass (in grams) of a bacterial culture over time using
MATHEMATICS · Multi-part · A Level · Mathematics · Exponentials and logarithms · Exponentials and logarithms
Problem
Biologists model the mass (in grams) of a bacterial culture over time using M(t)=Ae−kt, where A is the initial mass and k>0 is an unknown decay rate. The culture is measured every hour for six hours; the data are recorded below.
Time t (h)
0
1
2
3
4
5
6
Measured mass Mobs (g)
5.00
3.95
3.10
2.46
1.94
1.56
1.25
Because the initial reading is precise, set A=5.00 g. You must determine the decay rate k that best matches the remaining observations.
(a) Write an explicit expression S(k) for the total squared deviation between the model M(t)=5.00e−kt and the observed masses for t=1 through t=6.
(b) Derive S′(k) and set it equal to zero. Show all calculus steps leading to an equation that the optimal k satisfies.
(c) Using technology or justified numerical estimation, solve the equation from part (b) to three decimal places. State the value of k with appropriate units.
(d) Based on your value of k, predict the culture’s mass at t=8 h. Comment on the reliability of this prediction, considering the spacing of the data and the exponential model.