A patch-clamp record of a single channel lasts

PHYSICS · Multi-part · Fermi University Physics · Biophysics & Medical Physics · Molecular machines, transport and bioenergetics · Molecular machines, transport and bioenergetics

Forces, Machines and Signals, Ch Channels, pumps and the resting potential

Problem

A patch-clamp record of a single channel lasts 500 ms500\,\mathrm{ms}. The channel is open for a total of 150 ms150\,\mathrm{ms}, during 2525 separate open intervals (the record starts with the channel closed and ends with it open, so there are also 2525 closed intervals). ((a)) Find the open probability PoP_o. ((b)) Find the mean open time. ((c)) Find the mean closed time.

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