An amino-acid symporter carries one sodium ion ( ) into a cell for every solute…

PHYSICS · Subjective · Fermi University Physics · Biophysics & Medical Physics · Molecular machines, transport and bioenergetics · Molecular machines, transport and bioenergetics

Forces, Machines and Signals, Ch Channels, pumps and the resting potential

Problem

An amino-acid symporter carries one sodium ion (

n = 1

) into a cell for every solute molecule it transports. Sodium concentrations are

[\mathrm{Na}]_o = 140\,\mathrm{mM}

outside and

[\mathrm{Na}]_i = 15\,\mathrm{mM}

inside, and the membrane potential is

V = -70\,\mathrm{mV}

310\,\mathrm{K}

(

k_BT/e = 26.7\,\mathrm{mV}

). Find the maximum solute concentration ratio

[S]_i/[S]_o

this transporter can sustain at equilibrium.

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