In a reduced-calcium Ringer solution bathing a frog neuromuscular junction

PHYSICS · Multi-part · Fermi University Physics · Biophysics & Medical Physics · Bioelectricity, the senses and the physics of the body · Bioelectricity, the senses and the physics of the body

Forces, Machines and Signals, Ch The nerve impulse

Problem

In a reduced-calcium Ringer solution bathing a frog neuromuscular junction, motor nerve stimulation was repeated 150150 times. On 2525 of these trials no end-plate potential was detected (a failure). Assume quantal transmitter release follows a Poisson process. ((a)) Find the mean quantal content mm of the end-plate response. ((b)) Using this value of mm, predict how many of the 150150 trials should show a response of exactly two quanta.

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