PHYSICS · Multi-part · Fermi University Physics · Optics & Photonics · Biophysics & Medical Physics · Bioelectricity, the senses and the physics of the body
Forces, Machines and Signals, Ch Vision and photoreception: counting photons
Problem
A rod's dark current in darkness is about 20pA. Absorption of a single 505nm photon by rhodopsin reduces this current by about 1.2pA for approximately 0.8s before the current recovers (treat the response as a rectangular pulse of that height and duration for the estimate).
((a)) Estimate the number of elementary charges kept from crossing the rod's membrane by this one photon absorption (the gain of the single-photon response).
((b)) Express the energy of the absorbed 505nm photon in units of kBT at body temperature, 310K. State the assumptions used in each part.