A protein is tagged for active degradation with a half-life of
PHYSICS · Multi-part · Fermi University Physics · Mathematical Methods for Physics · Biophysics & Medical Physics · Genetic circuits, regulation and biological information
Forces, Machines and Signals, Ch Genetic circuits and biological pattern
Problem
A protein is tagged for active degradation with a half-life of 15min, in cells that divide every 40min. Assume dilution by growth and degradation act as independent first-order loss processes, so their rates add.
((a)) Calculate the total loss rate γ.
((b)) Calculate the half-time for the protein level to reach its new steady state after the gene is switched on.