A fluorescent reporter protein expressed in a population of identical bacteria has a…
PHYSICS · Multi-part · Fermi University Physics · Biophysics & Medical Physics · Genetic circuits, regulation and biological information · Genetic circuits, regulation and biological information
Forces, Machines and Signals, Ch Genetic circuits and biological pattern
Problem
A fluorescent reporter protein expressed in a population of identical bacteria has a mean copy number of 300 per cell and a variance of 3600.
((a)) Compute the Fano factor of this protein's copy number distribution.
((b)) Use the relation Fano ≈1+bburst for geometric translational bursts to estimate the mean burst size bburst (proteins made per mRNA).