An ion channel protein can sit in a closed conformation or in a partially unfolded…

PHYSICS · Subjective · Fermi University Physics · Thermal, Statistical & Complex Systems · Biophysics & Medical Physics · Physical foundations of the living cell

Life at Thermal Energy, Ch Entropy, free energy and the forces that counting produces

Problem

An ion channel protein can sit in a closed conformation or in a partially unfolded conformation whose energy is 4kBT4k_BT higher, at 298 K298\,\mathrm{K}. Treating the two conformations as the only two states available, calculate the ratio of the population in the higher-energy (unfolded) conformation to the population in the closed conformation.

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