A cell-surface receptor binds a hormone with dissociation constant

PHYSICS · Subjective · Fermi University Physics · Biophysics & Medical Physics · Macromolecules, membranes and cell architecture · Molecular machines, transport and bioenergetics

Life at Thermal Energy, Ch Entropy, free energy and the forces that counting produces

Problem

A cell-surface receptor binds a hormone with dissociation constant Kd=200 nMK_d = 200\,\mathrm{nM}. Calculate the fraction of receptors occupied when the hormone concentration in the surrounding fluid is 50 nM50\,\mathrm{nM}.

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