A chloride channel has open-state conductance

PHYSICS · Multi-part · Fermi University Physics · Electricity, Magnetism & Electromagnetism · Biophysics & Medical Physics · Molecular machines, transport and bioenergetics

Life at Thermal Energy, Ch The membrane: barrier, capacitor and pump

Problem

A chloride channel has open-state conductance g=8 pSg = 8\,\mathrm{pS}. The membrane potential is Vm=−50 mVV_m = -50\,\mathrm{mV} and the chloride Nernst potential is ECl=−90 mVE_{\rm Cl} = -90\,\mathrm{mV}. Model the open channel as obeying Ohm's law, i=g(Vm−ECl)i = g(V_m - E_{\rm Cl}). ((a)) Find the current ii through the open channel, in pA. ((b)) Find the number of chloride ions crossing per second.

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