A student is asked to find the Nernst potential of sodium at body temperature ( )

PHYSICS · Multi-part · Fermi University Physics · Biophysics & Medical Physics · Molecular machines, transport and bioenergetics · Molecular machines, transport and bioenergetics

Life at Thermal Energy, Ch The membrane: barrier, capacitor and pump

Problem

A student is asked to find the Nernst potential of sodium at body temperature (310 K310\,\mathrm{K}), using Na+\mathrm{Na^+} concentrations of 12 mM12\,\mathrm{mM} inside and 145 mM145\,\mathrm{mM} outside. Their working is shown below."kBT/e=26.7 mVk_BT/e = 26.7\,\mathrm{mV} at 310 K310\,\mathrm{K}. So ENa=kBTeln⁡ ⁣(cincout)=26.7 mV×ln⁡ ⁣(12145)=−66.6 mV.\begin{aligned} E_{\rm Na} &= \frac{k_BT}{e}\ln\!\left(\frac{c_{\rm in}}{c_{\rm out}}\right) \\ &= 26.7\,\mathrm{mV}\times\ln\!\left(\frac{12}{145}\right) \\ &= -66.6\,\mathrm{mV}. \end{aligned}" ((a)) Identify the error in the working. ((b)) Give the correct value of ENaE_{\rm Na}, to the nearest millivolt.

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