Transcription & RNA Processing
A 18-module path through transcription & rna processing, in study order from foundations to the frontier.
Modules
- RNA Polymerase and the Transcription Cycle
- Bacterial Promoters and the -10/-35 Elements
- Sigma Factors and Promoter Recognition
- Transcription Initiation and Promoter Escape
- Transcription Elongation and Proofreading
- Transcription Termination in Bacteria
- Eukaryotic RNA Polymerases I, II, and III
- General Transcription Factors and Assembly of the Preinitiation Complex
- The RNA Polymerase II CTD and Co-transcriptional Coupling
- The 5' Cap and Its Functions
- Splicing and the Spliceosome
- Alternative Splicing and Isoform Diversity
- 3' Cleavage and Polyadenylation
- RNA Editing
- mRNA Export and Stability
- Ribosomal and Transfer RNA Processing
- Self-Splicing Introns and Ribozymes
- The RNA World Hypothesis and Catalytic RNA