Protein Structure & Function
A 24-module path through protein structure & function, in study order from foundations to the frontier.
Modules
- Primary Structure and the Amino Acid Sequence
- The Peptide Bond and Its Partial Double-Bond Character
- The Ramachandran Plot and Backbone Dihedral Angles
- Levels of Protein Structural Organization
- The Alpha Helix
- Helix Stability and Amino Acid Propensities
- Beta Sheets and Beta Strands
- Turns, Loops, and Bends
- Supersecondary Structure and Motifs
- Noncovalent Forces That Stabilize Folded Proteins
- The Hydrophobic Effect and the Protein Core
- Tertiary Structure and the Fold
- Protein Domains and Structural Classification
- Fibrous Proteins
- Globular Proteins
- Protein Folding Pathways and Thermodynamics
- Molecular Chaperones and Assisted Folding
- Denaturation and Protein Stability
- Quaternary Structure and Subunit Assembly
- Myoglobin Structure and Oxygen Binding
- Hemoglobin Structure and Quaternary Change
- Cooperative Binding and Allostery
- The Bohr Effect and Allosteric Effectors
- Protein Purification and Analysis Strategies