Two biosynthetic routes are available for producing one mole of compound Z (ΔG° = +200 kJ mol⁻¹).
• Route 1: coupled to hydrolysis of 7 ATP → ADP (ΔG° per ATP = −30.5 kJ mol⁻¹)
• Route 2: coupled to hydrolysis of 4 ATP → AMP + PPi (ΔG° per ATP = −45.6 kJ mol⁻¹)
Ignoring additional cofactors, determine which route provides the more favorable overall ΔG° under standard conditions and calculate that overall ΔG°.