Glucose phosphorylation can be accomplished through the two steps below (values at 298 K)

CHEMISTRY · Subjective · AP · Chemistry · Thermodynamics and Electrochemistry · Thermodynamics and Electrochemistry

Problem

Glucose phosphorylation can be accomplished through the two steps below (values at 298 K). Glucose + PiP_i →\rightarrow Glucose-6-P  ΔG∘=+13.8 kJ mol−1\Delta G^\circ = +13.8\,\text{kJ mol}^{-1} ATP + H2_2O →\rightarrow ADP + PiP_i  ΔG∘=−30.5 kJ mol−1\Delta G^\circ = -30.5\,\text{kJ mol}^{-1} In one or two sentences, explain how combining these reactions leads to an overall process that is spontaneous under standard conditions.

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